• by perihelion_zero on 10/7/2024, 11:29:34 PM

    Been mucking around with huge doses of B Vitamins (especially B3/Niacin) and 5-HTP (a serotonin precursor). Both of those are rather, uh, effectful. 500mg+ Niacin will turn you red unless you're actually deficient. And you do not want to mess with the 5-HTP and alcohol at the same time, plus 5-HTP can cause some nasty side effects in some people.

    Seems like a nice way to have some weird dreams while probably improving my health (high dose B vitamins seem to do great things for mental disorder and the only apparent downside is colorful piss and possibly turning into a cherry).

    For people who don't do vita-drugs, there's always tea, coffee, chocolate, and matcha.

  • by cfcf14 on 10/8/2024, 7:00:32 AM

    L-theanine (200mg) with around 100-150mg of caffeine has an extremely noticeable, positive effect on my ability to focus, feeling of "well-situatedness", and overall calmness. L-theanine by itself doesn't seem to do much. Caffeine on its own wakes me but makes me feel jittery and anxious, so it's definitely an interaction effect. Taurine has a much smaller effect on calmness, sans interactions - often indistinguishable from any other mild focus exercise like box breathing or stretching.

  • by bagful on 10/7/2024, 5:25:33 PM

    For my biology, L-theanine (200 mg) rounds out caffeine by stamping out the anxiety-inducing effect. By itself it just gives me a headache sometimes.

  • by mentos on 10/7/2024, 6:06:22 PM

    I once was sitting at my desk and had this overwhelming calm come over me. I was trying to figure out what I had eaten that morning/afternoon and then realized the 2-3 'Just Chill' sodas in my trash my mom had gotten me contained L-Theanine. Was a pretty blind test but I wasn't able to reproduce it effectively with L-Theanine supplements I found on amazon.

  • by marmight on 10/7/2024, 5:15:48 PM

    I would have liked to have seen if there was any difference in the effects over time. I think it is easy to find something that helps with anxiety in the short term, but over enough time habituation, tolerance, and dependence can develop to most substances.

  • by binary132 on 10/8/2024, 1:55:51 PM

    Anecdotally, my theanine use correlated strongly with my development of terrible chronic migraines which lasted years. But I was also experiencing severe stress during that time, so it could just be that. However, when I stopped taking L-theanine, my headaches did lessen in severity and frequency, so there may be something there and I’ve heard others mention headache in relation to it.

  • by huuhee3 on 10/7/2024, 6:27:47 PM

    I tried an L-theanine supplement for anxiety. It had a notable short-term effect, but when I was off it my anxiety significantly worsened. Got better once I stopped taking it, so I guess it was a dependency kind of thing.

    So, I would say that it definitely has an impact. Perhaps it would have worked better with a smaller dose.

  • by wslh on 10/7/2024, 4:31:07 PM

    It is great the author highlights that green tea already includes L-theanine where it is common to read about buying supplements.

  • by Havoc on 10/8/2024, 12:06:34 PM

    Tried it too a didn’t go well. No immediate effect and then after a couple of days experienced severe emotional fragility. That “about to burst into tears“ type feeling. Quickly dropped that stuff

  • by ssebs on 10/7/2024, 4:56:53 PM

    I've taken L-theanine for anxiety before, and it seems to help. I'm not sure if it's a placebo or not, but either way it seems to help

  • by _DeadFred_ on 10/7/2024, 11:53:07 PM

    I don't really notice a change when I take theanine but the times when I have taken it consistently I notice I stop biting my fingernails.

    I just realized this week I haven't been biting my nails and from this popping up thought about it, went and checked, and the new magnesium drops I started taking have theanine.

  • by coreyh14444 on 10/8/2024, 7:39:44 AM

    Kindof softof related - I also "discovered" L-tyrosine effectively cured my Restless Leg Syndrome (RLS). The tl;dr version of that story is I used to take electrolytes for it and switched from the Heed brand regular version to the "extreme" version which didn't do anything for RLS, compared the ingredients and L-Tyrosine was the key. For going on 15 years now I take it daily before bedtime and it is effective 98% of the time. Bottom line is these amino acids deserve more attention and research.

  • by jvans on 10/7/2024, 4:28:46 PM

    fitbits and similar are fine for measuring awake vs asleep but really terrible at breaking up the stages

  • by ulnarkressty on 10/7/2024, 5:12:25 PM

    > This study was not blinded so there could be a placebo effect.

    Saved you a click.

  • by oigursh on 10/7/2024, 6:45:00 PM

    gwern.net has entered the chat